Does the Flu Vaccine Prevent Death?

Does the Flu Vaccine Prevent Death? by Eyal Shahar at Brownstone Institute THE LANCET Regional Health — Europe Dear Editor, My letter is concerned with a topic of utmost importance: The effect of the flu vaccine on flu-related death. That’s the ultimate endpoint of interest for vaccine effectiveness (VE) research, yet it is not captured in most studies that employ the test-negative design. Faksova et al. (January 2026) reported in your journal results from a large cohort study of the flu vaccine in 2024–2025 in elderly residents (age≥65) of three Nordic countries. The estimated VE against flu-related death was 63%, which corresponds to a risk ratio (RR) of 0.37. How robust is the result? What does...

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